¡Nuevo formato en sobres monodosis!, 50% descuento en tu primera compra (1 unidad). Cupón descuento->   PROMO50





  1. New Therapeutic Implications of Endothelial Nitric Oxide Synthase (eNOS) Function/Dysfunction in Cardiovascular Disease Andreas Daiber 1, Ning Xia 3, Sebastian Steven 1, Matthias Oelze 1, Alina Hanf 1, Swenja Kröller-Schön 1, Thomas Münzel 1,2 and Huige Li 3, Germany 2018


  1. Sirtuin 1/soluble guanylyl cyclase: a nitric oxide-independent pathway to rescue ageing-induced vascular dysfunction Rosa Suades and Francesco Cosentino* Cardiology Unit, Department of Medicine, Karolinska Institute and Karolinska University Hospital, Solna, 171 76 Stockholm, Sweden 2018


  1. Nitric oxide synthases: structure, function and inhibition Wendy K. ALDERTON*, Chris E. COOPER and Richard G. KNOWLES*1 *In Vitro Pharmacology Department, GlaxoSmithKline Research and Development, Medicines Research Centre, Gunnels Wood Road, Stevenage SG1 2NY, U.K., and Department of Biological Sciences, Central Campus, University of Essex, Wivenhoe Park, Colchester CO4 3SQ, U.K. 2001


  1. Glucagon-like peptide-1 activates endothelial nitric oxide synthase in human umbilical vein endothelial cells Li DING, Jin ZHANG* Department of Endocrinology, First Affiliated Hospital of China Medical University, Shenyang 110001, China 2012


  1. Zhou L, Zhu DY. Neuronal nitric oxide synthase: Structure, subcellular localization, regulation and clinical implications. 2009; 20(4): 223-30.


  1. Zinc regulates iNOS- derived nitricoxid eformation in endothelialcells Miriam M.Cortese-Krott a,b,n, LarissaKulakov a,c, ChristianOpländer c,VictoriaKolb-Bachofen b, Klaus-D.Kröncke d, ChristophV.Suschek b,c Germany 2014


  1. Miquel E, Farré R. Effects and future of casein phosphopeptides on zinc biovailability. Trends in FoodScience&Technology. 2007; 18(3): 139-143



  1. Fiorilli A, Perego S, Ferraretto F. Phosphopeptides of casein: Mineral carriers and potential nutraceutical. En: Casein: Production, Uses and Health Effects. Nova Science Publishers Inc. New York; 2012. p. 83-100.


  1. Whey protein hydrolysate and branched-chain amino acids downregulate inflammation-related genes in vascular endothelial cells Marine S. Da Silva Endocrinology and Nephrology, CHU de Québec, Canada G1V 4G2 2017


  1. Ballard KD, Bruno RS, Seip RL,  Quann EEVolk BMFreidenreich DJ, et al. Acute ingestion of a novel whey-derived peptide improves vascular endothelial responses in healthy individuals: a randomized, placebo controlled trial. 2009; 22(8): 34.


  1. Sánchez D, Kassan M, Contreras MM, Carrón R, Recio I, Montero MJ, Sevilla MA. Long-term intake of a milk casein hydrolyzate attenuates the development of hypertension and involves cardiovascular benefits. Pharmacol Res 2011, 63: 398-404


  1. Ginkgo biloba Extract: Mechanisms and Clinical Indications Bruce J. Diamond, PhD, Samuel C. Shiflett, PhD, Nancy Feiwel, MD, Robert J. Matheis, MA, Olga Noskin, BA, Jennifer A. Richards, BA, Nancy E. Schoenberger, PhD USA 2000


  1. Neuroprotective effects of Ginkgo biloba extract B.Ahlemeyer and J. Krieglstein*Institut für Pharmakologie und Toxikologie, Fachbereich Pharmazie der Philipps-Universität Marburg, Ketzerbach 63, 35032 Marburg (Germany), Fax: +49 6421-2828918, Germany 2003


  1. Bivalacqua TJ, Usta MF, Champion HC, Kadowitz PJ, Hellstrom WJ. Endothelial Dysfunction in Erectile Dysfunction: Role of the Endothelium in Erectile Physiology and Disease. Androl. 2003; 24(6): S17-37.


  1. eNOS function and dysfunction in the penis Biljana Musicki 1, Arthur L Burnett Exp Biol Medicine (Maywood) 2006


  1. eNOS-uncoupling in age-related erectile dysfunction J M Johnson, T J Bivalacqua, G A Lagoda, A L Burnett & B Musicki International Journal of Impotence Research 2011


  1. Testosterona, función endotelial, salud cardiovascular y androgenodeficiencia del varon añoso Testosterone, endothelial function, cardiovascular health and androgen deficiency in the old man R. Vela Navarrete, J. V. García Cardoso, M. Pardo Montero, P. Jiménez Máteos-Cáceres y A. López Farré. UCM 2009


  1. Endothelial nitric oxide synthase in the microcirculation Xiaohong Shu1,2 • T. C. Stevenson Keller IV2,3 • Daniela Begandt2 Joshua T. Butcher2 • Lauren Biwer2,3 Alexander S. Keller2,4 • Linda Columbus5 • Brant E. Isakson2,3 USA 2015


  1. Aversa A, Bruzziches R, Francomano D, Natali MGareri PSpera G. Endothelial dysfunction and erectile dysfunction in the aging man. International Journal of Urology. 2010;17(1): 38-47.


  1. Sexual dysfunction and the ageing male Kevan Wyliea,b ,1, Gemma Kenneyb,1 a Porterbrook Clinic, Sexual Medicine, 75 Osborne Road, Sheffield, South Yorkshire S11 9BF, United Kingdom The University of Sheffield, Western Bank, Sheffield S10 2TN, UK 2010


  1. Nitric oxide and penile erectile function Noboru Todaa,b,T, Kazuhede Ayajikia, Tomio Okamuraa aDepartment of Pharmacology, Shiga University of Medical Science, Otsu, Japan bToyama Institute for Cardiovascular Pharmacology Research, 7–13, 1-Chome, Azuchi-machi, Chuo-ku, Osaka 541-0052, Japan 2005


  1. Endothelial Dysfunction in Erectile Dysfunction: Role of the Endothelium in Erectile Physiology and Disease TRINITY J. BIVALACQUA. From the Departments of Urology and †Pharmacology, Tulane University School of Medicine, New Orleans, Louisiana; and the §Department of Medicine, Division of Cardiology, Johns Hopkins Hospital, Baltimore, Maryland 2003.


  1. Vela R, Navarrete JV, García M, Pardo M, Jiménez P, López A. Testosterona, función endotelial, salud cardiovascular y andrógeno deficiencia en el varón añoso. Arch. Esp. Urol. 2009; 62(3): 173-8.


  1. Martínez-Salamanca JI, Martínez-Ballesteros C, Portillo L, Gabancho S, Moncada I, Carballido J. Fisiología de la erección. Arch. Esp. Urol. 2010; 63(8): 581-588


  1. The role of nitric oxide in erectile dysfunction: implications for medical therapy Arthur L Burnett 1 J Clin Hypertens (Greenwich). 2006


  1. Santos RF, Galduroz JC, Barbieri A, Castiglioni MLYtaya LYBueno OF. Cognitive Performance, SPECT, and Blood Viscosity in Elderly Non-Demented People Using Ginkgo Biloba. 2003; 36(4): 127-33.


  1. Chauhan NS, Sharma V, DixitVK, Thakur M. A review on plants used for improvement of sexual performance and virility. BioMed Research International 2014; article ID 868062.


  1. Chen J, Wollman Y, Chernichovsky TIaina ASofer MMatzkin H. Effect of oral administration of high-dose nitric oxide donor l-arginine in men with organic erectile dysfunction: results of a double-blind, randomized placebo-controlled study. BJU International. 1999; 83(3): 269-73


  1. Vitamin D and Male Sexual Function: A Transversal and Longitudinal Study Giacomo Tirabassi ,1 Maurizio Sudano, 2 Gianmaria Salvio,1 Melissa Cutini,1 Giovanna Muscogiuri,3 Giovanni Corona,4 and Giancarlo Balercia Italia 2018


  1. The effect of low vitamin D status on sexual functioning and depressive symptoms in apparently healthy men: a pilot study Robert Krysiak1 Anna Szwajkosz Bogusław Okopień1 Received: 23 October 2017 / Revised: 5 March 2018 / Accepted: 29 April 2018 / Published online: 5 July 2018 © Macmillan Publishers Limited, part of Springer Nature 2018


  1. Acute L-Arginine supplementation does not increase nitric oxide production in healthy subjects Thiago Silveira Alvares1,2, Carlos Adam Conte-Junior1, Joab Trajano Silva1 and Vânia Margaret Flosi Paschoalin1 Alvares et al. Nutrition & Metabolism 2012, 9:54 Brazil


  1. L-Arginine and vascular diseases: lights and pitfalls! Rocco Salvatore Calabrò1, Placido Bramanti1, Giuseppe Gervasi2 1 IRCCS Centro Neurolesi Bonino-Pulejo, Messina; 2 Via Roma, 98050 Malfa (ME) 2014


  1. The nitric oxide pathway in the human prostate: clinical implications in men with lower urinary tract symptoms. World J Urol (2008) 26:603–609 George T. Kedia Stefan Ückert Udo Jonas Markus A. Kuczyk · Martin Burchardt


  1. Lower Urinary Tract Symptoms and Sexual Dysfunction in Male: A Systematic Review and Meta-Analysis. Song G. Frontiers in Medicine, 28 May 2021


  1. The association of endothelial nitric oxide synthase (eNOS) G894T gene polymorphism with responsiveness to a selective a1-blocker in men with benign prostatic hyperplasia related lower urinary tract symptoms Yung-Chin Lee Kaohsiung Medical University. Taiwan 2016


  1. Efficacy and Safety of Serenoa repens Extract among Patients with Benign Prostatic Hyperplasia in China: A Multicenter, Randomized,Double-blind, Placebo-controlled Trial. Zhixian Wang, Xiaoyong Zeng. Urology 2019


  1. Nitric oxide/cGMP-mediated effects in the outflow region of the lower urinary tract is there a basis for pharmacological targeting of cGMP? Petter Hedlund. World J Urol (2005) 23: 362–367


  1. Overview of comments received on European Union herbal monograph on Serenoa repens (W. Bartram) Small, fructus (EMA/HMPC/280079/2013. Committee on Herbal Medicinal Products (HMPC) EMA/HMPC/278488/2015




  1. Lower urinary tract symptoms/benign prostatic hypertrophy and vascular function: Role of the nitric oxide–phosphodiesterase type5–cyclic guanosine 30,50-monophosphate pathway Yukihito Higashi. International Journal of Urology (2017) 24, 412—424


  1. Revisión sobre la experiencia y evidencias del Pygeum africanum en Urología J. Salinas-Casado, J.M. Cozar-Olmod. Actas Urológicas Españolas 2019


  1. Serenoa repens, selenium and lycopene to manage lower urinary tract symptoms suggestive for benign prostatic hyperplasia. Andrea Salonia. Expert Opinion on Drug Safety 2016


  1. Survivin and NAIP in Human Benign Prostatic Hyperplasia: Protective Role of the Association of Serenoa repens, Lycopene and Selenium from the Randomized Clinical Study Giuseppe Morgia International Journal of Molecular Sciences 2017


  1. Prevalence, Burden, and Treatment of Lower Urinary Tract Symptoms in Men Aged 50 and Older: A Systematic Review of the Literature. Amy Y. Zhang, PhD and Xinyi Xu, RN, BSN. SAGE Open Nursing 2018


  1. Flavonoid and Botanical Approaches to Prostate Health AARON E. KATZ, M.D. THE JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE 2002


  1. Nutraceutical treatment and prevention of benign prostatic hyperplasia and prostate cancer. Arrigo F.G. Cicero Annabella Vitalone. Archivo Italiano di Urlogia e Andrologia 2019


  1. Ingestion of a nitric oxide enhancing supplement improves resistance exercise performance Scott Mosher Journal of Strength and Conditioning Research 2016


  1. The Effect of Nitric-Oxide-Related Supplements on Human Performance Raul Bescos Antoni Sureda, Josep A. Tur and Antoni Pons. Sports Med 2012


  1. Nutritional and Supplementation Strategies to Prevent and Attenuate Exercise-Induced Muscle Damage: a Brief Review Patrick S. Harty, Megan L. Cottet, James K. Malloy and Chad M. Kerksick Sports Medicine – Open (2019)


  1. Dietary Supplements for Health, Adaptation, and Recovery in Athletes. Rawson ES, International Journal of Sport Nutrition and Exercise Metabolism 2018


  1. Effects of Rhodiola rosea supplementation on mental performance, physical capacity, and oxidative stress biomarkers in healthy men Ewa Jówko ScienceDirect 2016


  1. Rhodiola rosea for physical and mental fatigue: a systematic review Sana Ishaque Complementary and Alternative Medicine 2012


  1. Gender differences and access to a sports dietitian influence dietary habits of collegiate athletes. Michael V. Hull. Journal of the International Society of Sports Nutrition (2016)


  1. Can Magnesium Enhance Exercise Performance? Yijia Zhang ID Pengcheng Xun1 ID, Ru Wang , Lijuan Mao and Ka He, NUTRIENTS 2017


  1. Dietary Supplement with a Combination of Rhodiola Crenulata and Ginkgo Biloba Enhances the Endurance Performance in Healthy Volunteers. ZHANG Zhang-jin Chin J Integr Med 2009


  1. Sports Supplements Pearls and Pitfalls Katherine M. Edenfield, MD Department of Community Health and Family Medicine, University of Florida. Prim Care Clin Office Pract – (2019)


  1. Resistance Training, Antioxidant Status, and Antioxidant Supplementation. Ismaeel A. International Journal of Sport Nutrition and Exercise Metabolism 2019


  1. Research in Nutritional Supplements and Nutraceuticals for Health, Physical Activity and Performance: Moving Forward. Wendy E. Ward Department of Kinesiology, Brock University. Canada. 2019


  1. Dietary Supplements and Team-Sport Performance David Bishop Victoria University, Melbourne, Victoria, Australia. Sports Med 2010


  1. Nutrition and Supplement Update for the Endurance Athlete: Review and Recommendations Kenneth Vitale. Nutrients 2019


  1. Use of Performance-Enhancing Endocrine Drugs (Doping) in Competitive and Recreational Sports Activity. Ergogenic Aids and Supplements Marisa Porrini Cristian Del Bo. Sports Endocrinology 2016


  1. Expressions of vaginal endothelial nitric oxide synthase and phosphodiesterase 5 in female sexual dysfunction: a pilot study Kang Jun Cho1 & Kyu-Sung Lee2 & Myung-Soo Choo3 & Ju Tae Seo4 & Jang Hwan Kim5 & Jong Bo Choi6 & Seung-June Oh7 & Joon Chul Kim1 Korea 2016


  1. Endothelial Nitric Oxide Synthase Regulation in Female Genital Tract Structures Biljana Musicki, PhD, Tongyun L. Burnett, MD Department of Urology, The Johns Hopkins University, Baltimore, MD, USA


  1. Pause menopause with Rhodiola rosea, a natural selective estrogen receptor modulator Patricia L.Gerbarg Phytomedicine 2016


  1. A Pilot Study of Rhodiola rosea for Generalized Anxiety Disorder (GAD) ALEXANDER BYSTRITSKY MD. THE JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE 2008


  1. Rhodiola rosea in Subjects with Prolonged or Chronic Fatigue Symptoms: Results of an Open-Label Clinical Trial Yevgeniya Lekomtseva. Complement Medicine Research 2017


  1. Female Sexual Dysfunction: Principles of Diagnosis and Therapy. Rachel N. Pauls, MD,Steven D. Kleeman, MD, and Mickey M. Karram, MD 2005


  1. Expressions of vaginal endothelial nitric oxide synthase and phosphodiesterase 5 in female sexual dysfunction: a pilot study. Kang Jun Cho1 & Kyu-Sung Lee2 & Myung-Soo Choo3 & Ju Tae Seo4 & Jang Hwan Kim5 & Jong Bo Choi6 & Seung-June Oh7 & Joon Chul Kim1. 2016


  1. Sexualidad en la menopausia Rosa Simbaña S,1 Eliana Félix L,2 Ximena Arteaga R.3 Médica Residente de Postgrado Gineco-Obstetricia,2 Médica Gineco-Obstetra,3 Enfermera Rural,Hospital Gineco-Obstétrico “Isidro Ayora”, Quito-Ecuador


  1. DISFUNCIÓN SEXUAL FEMENINA Artículo de actualización cle FEMALE SEXUAL DYSFUNCTION Dres. Bechara, A.*; Casabé, A.*; Bertolino, V.** 2002


  1. The effect of vitamin D supplementation on sexual functioning and depressive symptoms in young women with low vitamin D status, Endokrynologia Polska DOI: 10.5603/EP a2018.0013 Tom/Volume 69; Numer/Number 2/2018 Poland


  1. Biochemical Factors Modulating Female Genital Sexual Arousal Physiologyjsm_1903 2925.2946 Abdulmaged M. Traish, PhD,* Ella Botchevar, MA,† and Noel N. Kim, PhD Boston University School of Medicine 2010


  1. Expression and distribution of key enzymes of the cyclic GMP signaling in the human clitoris: relation to phosphodiesterase type 5 (PDE5) S U¨ ckert1, M Oelke1, K Albrecht, D Breitmeier MA Kuczyk and P Hedlund Sweden 2011


  1. Nitric Oxide May Mediate Nipple Erection MURAT TEZER, YASEMIN OZLUK, ONER SANLI, OKTAR ASOGLU, AND ATES KADIOGLU. From the Department of Urology, Pathology and General Surgery, Istanbul University Istanbul Faculty of Medicine, Istanbul, Turkey 2011


  1. The neurovascular mechanism of clitoral erection: nitric oxide and cGMP-stimulated activation of BKCa channels FERRANTE S. GRAGASIN, EVANGELOS D. MICHELAKIS, Department of Medicine (Cardiology) and the Vascular Biology Group, University of Alberta, Edmonton, Canada 2004


  1. Endothelial Nitric Oxide Synthase Regulation in Female Genital Tract Structures Biljana Musicki, PhD, Tongyun Liu, MS, Gwen A. Lagoda, MS, Trinity J. Bivalacqua, MD,PhD, Travis D. Strong, BA, and Arthur L. Burnett, MD Department of Urology, The Johns Hopkins University, Baltimore, MD, USA 2009


  1. Female Sexual Dysfunction: Therapeutic Options and Experimental Challenges Kyan J. Allahdadi1, Rita C.A. Tostes1,2, and R. Clinton Webb1 1 Department of Physiology, Medical College of Georgia, Augusta, Georgia, USA 2 Department of Pharmacology, University of Sao Paulo, Sao Paulo, SP, Brazil 2009


  1. Fisiología de la respuesta sexual femenina: actualización Manuel Mas Departamento de Fisiología y CESEX. Facultad de Medicina. Universidad de La Laguna. España 2007


  1. Nitric oxide interacts with monoamine oxidase to modulate aggression and anxiety- like behaviour. Héctor Carreño Gutiérreza, University of Leicester UK 2016


  1. The role of nitric oxide (NO) donors in anxiety. Lights and shadows Nikolaos Pitsikas. University of Thessaly. Greece 2018



  1. Role of nitric oxide in altered nociception and memory following chronic stress. Physiology & Behavior Masoud Nazeri Iran 2014


  1. Possible involvement of nitric oxide mechanism in the neuroprotective effect of rutin against immobilization stress induced anxiety like behaviour, oxidative damage in mice Lalit Machawal University of Panjab India 2014


  1. Nitric oxide-mediated anxiolytic-like and antidepressant-like effects in animal models of anxiety and depression. A. Spiacci. University of Mariga Brasil 2007



  1. Role of Nitric Oxide in Stress-Induced Anxiety: From Pathophysiology to TherapeuticTarget A. Kumar. Panjab University India 2017


  1. Nitric Oxide and Anxiety K. Gulati. University of Delhi, India 2002A Pilot Study of Rhodiola rosea for Generalized Anxiety Disorder (GAD) ALEXANDER BYSTRITSKY, Department of Psychiatry, University of California USA 2008


  1. The Effects of Rhodiola rosea L. Extract on Anxiety, Stress, Cognition and Other Mood Symptoms. Mark Cropley University of Surrey UK 2008


  1. Behavioural Effects of the American Traditional Plant Eschscholzia californica: Sedative and Anxiolytic Properties Alain Rolland. Universtity of Metz Francia 1990


  1. Anxiolytic activity of aerial and underground parts of Passiflora incarnate Kamaldeep Dhawan. University of Panjab India. 2001


  1. Neuroprotective effects of Ginkgo biloba extract B.Ahlemeyer and J. Krieglstein University of Philipps Germany, 2003


  1. Plants and the central nervous system. E.A. Carlini University of Sao Paulo 2003


  1. Effects of Traditionally used anxiolytics Botanicals on enzymes of the GABA. R Award. University of Otawa. Canada. 2007


  1. Plant-Based Medicines for Anxiety Disorders, Part 2: A Review of Clinical Studies with Supporting Preclinical Evidence. Jerome Sarris. University of Melburne. Australia. 2013 Pilot trial of Melissa officinalis L. leaf extract in the treatment of volunteers suffering from mild-to-moderate anxiety disorders and sleep disturbances Julien Cases Mediterr J Nutr Metab (2011)


  1. Pilot trial of Melissa officinalis L. leaf extract in the treatment of volunteers suffering from mild-to-moderate anxiety disorders and sleep disturbances Julien Cases Mediterr J Nutr Metab France (2011)